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Does Weed Make You Poop?

  • Writer: Aaron Killion
    Aaron Killion
  • Jun 17
  • 4 min read

Cannabis affects your digestive system through your body's endocannabinoid system, which controls gut movement, inflammation, and bowel regularity.


Cannabis does appear to help some people poop. Many medical marijuana patients notice changes in their bathroom habits after consuming it. However, these changes are not the same for everyone. 


The effects depend on tolerance, the way you consume cannabis, the strain, and your health. Understanding how weed affects digestion will help you be better prepared for the effects. 


How Cannabis Affects Digestion

Cannabis interacts with the CB1 and CB2 receptors in your gut. They help regulate bowel movements and inflammation. 


THC acts on CB1 receptors in your stomach and intestines. This sometimes slows digestion. For some cannabis patients, this may lead to constipation. For others, it speeds up their bowel movements. 


Immediate Digestive Effects of Weed

Weed often kicks in fast, which may lead to marijuana-induced diarrhea. Some people feel the urge to poop right after using it, and for some it happens within hours.


THC may make your gut muscles contract. People who are new to cannabis usually feel this more. Over time, your body may get used to it.


THC enters your bloodstream through your lungs when you smoke or vape cannabis. This may make you feel the high and the gut effects within minutes. Edibles take longer to have an effect because your body has to digest them first. They usually kick in after around 30 minutes to two hours, and their effects last much longer.


Long-Term Effects on Digestive Health

Regular cannabis use may lead to tolerance. Your body may become less responsive to the same dose over time. 


This may change how cannabis influences your digestive system.


Tolerance Development

Daily cannabis consumption may build tolerance to THC’s psychoactive and digestive effects. Some long-term consumers report experiencing constipation as their bodies become accustomed to regular cannabis use.


Chronic Use Considerations

Chronic heavy cannabis use may disrupt the endocannabinoid system, potentially causing digestive irregularities in some patients.


Medical Marijuana for Digestive Conditions 

Medical marijuana is approved by the state of Arizona for some digestive illnesses, seen in the state’s list of qualifying conditions for a medical card.


Qualifying Digestive Conditions

Crohn's disease is an AZ qualifying condition for medical marijuana. Ulcerative colitis and irritable bowel syndrome are not explicitly listed as qualifying conditions. However, they are covered under the severe nausea category. 


Crohn's Disease and Cannabis

Cannabis has shown promise in managing several Crohn's symptoms. The endocannabinoid system helps regulate gut inflammation. CBD, in particular, may reduce intestinal inflammation  and support intestinal healing. THC may help with pain and appetite stimulation.


Many Crohn's patients report improved bowel regularity, fewer flare-ups, and decreased pain when taking medical cannabis. Cannabis may also help manage the stress and anxiety that may worsen Crohn's symptoms.


Ulcerative Colitis Support

Cannabis may help ease ulcerative colitis symptoms by calming inflammation and supporting colon healing. CBD-rich strains are often preferred as they may reduce cramping and bathroom urgency without strong psychoactive effects.


Irritable Bowel Syndrome (IBS) Relief

IBS patients often find relief with cannabis. Patients who consumed cannabinoids reported significant improvements in abdominal pain, discomfort, nausea, diarrhea, appetite, and overall well-being.


Different cannabinoid profiles may help with different IBS symptoms:


  • High-CBD strains for anti-inflammatory effects

  • Balanced THC:CBD ratios for comprehensive symptom management

  • Specific terpene profiles for targeted relief


Factors Affecting Cannabis and Digestion

The way cannabis affects digestion depends on the strain, dosage, and how you consume it.  


Strain and Cannabinoid Profiles

Rather than simple indica/sativa classifications, specific cannabinoid ratios determine the effects you experience:


  • High-THC strains may slow gut motility. 

  • CBD-dominant strains often promote regular bowel movements. 

  • Products with a balanced THC and CBD ratio provide comprehensive benefits.

  • Important terpenes include myrcene (potentially sedating), limonene (may support digestion), and pinene (anti-inflammatory).


How Much You Take and How You Take It

Micro-doses (2.5 mg to 5 mg of THC) produce subtle effects, while standard doses (5 mg to 15 mg) create more noticeable changes. High doses (15 mg+) may cause significant digestive effects.


Consumption methods may vary in onset and duration:


  • Smoking/vaping: Fast-acting, 1 to 3 hours in duration

  • Edibles: Slower onset, 4 to 8 hours in duration

  • Tinctures: Precise dosing, faster sublingual absorption


Managing Cannabis and Your Gut

Managing cannabis use wisely can help support your gut health and minimize any potential digestive issues. 


Avoiding Problems

Drink plenty of water. Aim for 8 to 10 glasses daily since THC may dry you out a bit. Eat lots of fiber from whole grains, fruits, and veggies. Stay active because exercise helps your gut move, and consider probiotics to keep your gut bacteria happy. 


Timing It Right

Consume cannabis when you’re ready to handle any digestive surprises. Try CBD products during the day for gut support without getting high, and save your THC for the evening when you’re home. 


What’s Coming Next 

Researchers are still figuring out the best cannabinoid combinations for different gut problems. They continue to study the long-term effects and work on personalized cannabis treatments. 


Recent studies show that preparations combining CBD and THC show promise in mitigating gut symptoms through their anti-inflammatory and motility-enhancing effects. Scientists are working on optimal dosages. This is promising for conditions like Crohn’s disease.


Stay Safe

Always talk to your doctor before trying cannabis. It’s especially important if you have health issues or take medications. Cannabis products aren’t FDA-approved for digestive problems and may have side effects or interact with other drugs. 


Medical Marijuana for Your Digestive Health 

Cannabis affects everyone’s digestive system differently. Your body’s response depends on the strain, dosage, and your gut health. Some people experience immediate bathroom urges after use. Others notice more regular bowel movements over time. 


People with digestive conditions like Crohn's disease or IBS may find cannabis helpful for managing symptoms. It's not a cure-all solution. Different strains and doses produce different effects on your body. With the right medical guidance, it could be a game-changer for managing digestive issues.


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