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THC for PMDD

  • Writer: Aaron Killion
    Aaron Killion
  • May 19
  • 4 min read

Updated: Jun 3

Cannabis, specifically THC, may offer a calming anchor for women seeking relief for mood, pain, sleep

, and more.


PMDD (premenstrual dysphoric disorder) can feel like a storm of emotional and physical discomfort that disrupts daily life. Cannabis can be a great alternative way to help with the effects of PMDD. Let’s explore how cannabis might support PMDD symptoms.


About Premenstrual Dysphoric Disorder (PMDD)

PMDD is a severe, disruptive form of PMS disorder that impacts emotional and physical health.


PMDD's symptoms include severe depression, overwhelming anxiety, and intense physical discomfort. Symptoms typically arise 7-10 days pre-menstruation and ease shortly after bleeding starts. 


Harvard’s Health Blog suggests that PMDD may develop when the brain's mood-regulating areas, which are highly sensitive to estrogen and progesterone, react abnormally to hormonal changes, disrupting key neurotransmitter systems.


Conventional PMDD Treatment Options

Doctors offer multiple traditional strategies to manage PMDD symptoms by regulating hormones and brain chemicals.


Common treatments include:


  • Hormonal treatments: Birth control to stabilize hormonal swings

  • Antidepressants: SSRIs like fluoxetine, especially during the luteal phase

  • Anti-anxiety medications: Short-term benzodiazepine use

  • Lifestyle modifications: Exercise, nutrition, stress management

  • Nutritional supplements: Calcium, magnesium, vitamin B6


While these options help, side effects along with incomplete relief push some women to explore medical marijuana as an alternative.


How Cannabis Stands Out for PMDD Relief

Cannabis may offer PMDD relief by working with the body's endocannabinoid system to balance mood, pain, and sleep. 


Pain Relief

Cannabis reduces inflammation. This may help ease pain, lessen bloating, and improve overall mood stability.


Mood Regulation

By boosting dopamine and calming stress centers, THC alleviates emotional turbulence. Research from Washington State University reported that cannabis users experienced a 58% perceived reduction in anxiety and a 50% perceived decrease in depression following cannabis use.


Better Sleep


How CBD Works for PMDD

CBD works alongside THC to enhance these benefits without causing a "high."


Potential Benefits of Cannabis for PMDD

Cannabis may offer a natural, multi-symptom solution that surpasses some traditional treatments.


For MMJ patients, the benefits of cannabis for PMDD include:


  • Managing physical, emotional, and sleep issues simultaneously

  • Fast-acting symptom control

  • Fewer side effects than SSRIs or hormonal drugs

  • Customizable treatment plans

  • A plant-based alternative approach


If you’re interested in alternative cannabis treatments for PMDD, keep your medical marijuana card up to date to access legal cannabis without paying the 16% excise tax in Arizona.


How to Take Cannabis for PMDD

Choosing the right strain and delivery method makes a big difference in relief outcomes.


Recommended Strains

Specific strains target PMDD’s range of symptoms effectively:


  • Granddaddy Purple: Excellent for sleep and pain

  • Blue Dream: Lifts mood while easing physical discomfort

  • Harlequin: High-CBD option for daytime symptom control

  • Northern Lights: Ideal for evening anxiety and insomnia


Tip: Consider trying the Best Weed Strains for Pain Relief if you experience severe menstrual pain.


Effective Consumption Methods

Selecting the right method depends on how fast and how long you want relief.


  • Vaping/smoking: Rapid onset

  • Tinctures: Fast (15-45 minutes) and discreet

  • Edibles: Slow onset but long-lasting

  • Topicals: Target localized pain


You can also combine methods for layered symptom control.


Considerations and Precautions

Using THC comes with responsibilities. It's important to stay informed about side effects, drug interactions, and tolerance concerns.


Side Effects

Potential side effects may include dry mouth, bloodshot eyes, memory blips, and heightened anxiety at high doses.


Drug Interactions

THC may interfere with blood thinners, sedatives, antidepressants, and other medications. Always seek advice from a healthcare provider before taking THC for PMDD if you take any prescription or over-the-counter drugs.


Tolerance Concerns

Frequent THC use can lead to reduced effects. Cycling usage during different menstrual phases can help avoid tolerance buildup.


Terpenes for Specific PMDD Symptoms

Terpenes amplify the effects of cannabis and can fine-tune PMDD symptom relief.


Key terpenes include:


  • Myrcene: Myrcene calms muscles and promotes sleep.

  • Limonene: Limonene uplifts mood and combats emotional lows.

  • Linalool: Linalool eases anxiety and stress.

  • Beta-caryophyllene: Beta-caryophyllene reduces bloating and inflammation.


Ask your budtender about terpene profiles for tailored results.


Integrating THC With Other PMDD Treatments

Combining THC with traditional and holistic therapies often yields the best outcomes.


Holistic PMDD management might include:


  • Regular exercise and mindfulness practices

  • Anti-inflammatory diet plans

  • Essential supplements like calcium and magnesium

  • SSRIs or hormonal contraceptives (when needed)

  • Cognitive behavioral therapy (CBT)


It’s also important to consider cannabis safety for specific groups. For new moms, see  Marijuana and Breastfeeding to understand safety guidelines. If you're pregnant and not sure about eligibility, read Can You Get a Medical Card When Pregnant? 


FAQs About THC for PMDD

What is premenstrual dysphoric disorder (PMDD)?

PMDD is a severe type of premenstrual syndrome (PMS) that brings intense emotional symptoms like irritability, anxiety, and depressed mood. It can also bring about symptoms (about a week or so before your period) such as bloating, headaches, and joint pain. These symptoms usually ease once your period begins.


How does THC help with PMDD symptoms?

THC interacts with the body's natural systems that regulate various functions like mood, sleep, and pain. Many women report that using THC during PMDD helps ease physical pain, calm emotional symptoms, and lift their overall mood. It may help restore a sense of positive mood when things feel overwhelming.


What are the risks of cannabis use for PMDD?

It's important to be mindful of how much cannabis you consume. Using high quantities of cannabis over time increases the risk of cannabis use disorder, where someone feels they can't cut back even if it's affecting their life. Side effects like dry mouth, memory lapses, or even more anxiety might show up, especially with heavy or frequent use.


Which cannabis strains or products work best for PMDD?

Strains like Blue Dream or Granddaddy Purple could help with both emotional and physical symptoms, while high-CBD options like Harlequin are great for anxiety without a strong high. Whether you choose vaping, tinctures, or edibles depends on how quickly and how long you want relief.


Cannabis Could Be a Game-Changer for PMDD

PMDD can significantly impact a woman’s physical, psychological, and social well-being. Cannabis is a game-changer for women looking for alternative methods to ease symptoms. 


Finding the right strains, methods, and dosages, preferably under professional guidance, could make PMDD symptoms more manageable. Although cannabis therapy involves trial and error, the path toward physical comfort, emotional balance, and improved well-being is worth pursuing.


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